Mission and


The mission of Biomass Conversion and Bioprocess Technology group is to develop innovative solutions that can accelerate the development of a bioeconomy.


The ultimate goal of our research is to create a better future, where our resources are used more consciously, the environment is preserved, and our needs are fulfilled in a more efficient, economic and responsible way.

Ongoing projects

Development of advanced co-cultivation systems for an improved fermentation performance of complex substrates. 2020 – 2023.    

Understanding and overcoming physiological stress responses in Yarrowia lipolytica to dissolved O2 and CO2 in fermentation processes. 2019 – 2022. 


Development of a biotechnological process for the production of the antileukemic biopharmaceutical recombinant L-asparaginase: Optimization and economic feasibility study. 2019 – 2022.


WASTE2ENERGY: Integration of supercritical technologies and anaerobic digestion through an automated system for the production of biofuel precursors. 2019 – 2024. 


Process design, optimization and supply chain analysis for biotechnological production of xylitol. 2018 – 2021. 


Development of an innovative bioprocess for the valorization of lignocellulosic fibers by integrating biomass conversion, cell factory optimization and bioreactor engineering. 2018 – 2020. 


Development of technological strategies and sustainability analysis for the production of ethanol and value-added co-products in Uruguay. 2018 – 2020. 


Lipids and carotenoids production by oleaginous yeasts from lignocellulose biomass. 2017 – 2020. 


Bioprocess development using non-conventional yeasts and biomass hydrolysates. 2016 – 2020. 


Development of biorefineries using brewer´s spent grains as feedstock (BSG Refinery). 2016 – 2020. 

Meet the Team

Solange I. Mussatto
Group Leader
Giuliano M. Dragone
Senior Fermentation Scientist
Celina K. Yamakawa
Zhijia Liu
PhD Student
Lucas van der Maas
PhD Student
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Sirinapa Sasanam
PhD Student

External Members (co-supervision)

Larissa Pereira Brumano (Postdoc) – University of São Paulo (USP), Brazil 


Fernando Bonfiglio (PhD student)– University of the Republic (UdelaR), Uruguay

Bianca Consorti Bussamra (PhD student) – University of Campinas (UNICAMP), Brazil/Delft University of Technology (TU Delft), The Netherlands

Nikolaus Vollmer (PhD student) – Technical University of Denmark (DTU)

William Gustavo Sganzeria (PhD student) – University of Campinas (UNICAMP), Brazil 

Henrique Di Domenico Ziero (MSc student) – University of Campinas (UNICAMP), Brazil

Former Members

Bram Kerssemakers – Technical University of Denmark (DTU) – 2020

Jasper Driessen – Technical University of Denmark (DTU) – 2020

Diego Grumbach – ENSTBB Bordeaux INP, France – 2020


Ilaria d'Imperio – University of Bari Aldo Moro (UniBa), Italy – 2020

Francesca Natalizio – University of Bari Aldo Moro (UniBa), Italy – 2020

Anna Carolina Piazentin – University of São Paulo (USP), Brazil – 2020

Francesco Reggianini – University of Milan (UniMi), Italy – 2020

Eric Ebert – Beuth University of Applied Sciences Berlin (BHT Berlin), Germany – 2020

Marlene Fels – Beuth University of Applied Sciences Berlin (BHT Berlin), Germany – 2020


Luana de Fátima Alves – University of São Paulo (USP), Brazil – 2019


Kittipong "Nat" Rattanaporn – Kasetsart University (KU), Thailand – 2019

Ratthapong "Mai" Meesupthong – Kasetsart University (KU), Thailand – 2019

Philip Sørensen – Technical University of Denmark (DTU) – 2019

Jesper Jensen – Technical University of Denmark (DTU) – 2019

Jules Dior – ESPCI Paris, France – 2019

Fen Qin – Technical University of Denmark (DTU) – 2019

Ioannis Tsontzos – Technical University of Denmark (DTU) – 2019

Emilia Savioli López – University of Campinas (Unicamp), Brazil – 2019

Georgios Moukanakis – Technical University of Denmark (DTU) – 2018

Alexandra Nastouli – Technical University of Denmark (DTU) – 2018

Perikles Marios Sotiris – National Technical University of Athens (NTUA), Greece – 2018

Pablo Doménech Martínez – Technical University of Denmark (DTU) – 2018

Mikkel Reith Mahler – Technical University of Denmark (DTU) – 2018

Laura Kastell – Technical University of Denmark (DTU) – 2018

Astrid Zedlitz Johansen – Technical University of Denmark (DTU) – 2018

Marco Cassano – University of Bari Aldo Moro (UniBa), Italy – 2018

Ignacio Sánchez Moguel – University of São Paulo (USP), Brazil – 2017

Irving Flores Aviles – Wageningen University & Research (WUR), The Netherlands – 2017

Selected publications

Liu, Z; van den Berg, C; Weusthuis, RA; Dragone, G; Mussatto, SI. Strategies for an improved extraction and separation of lipids and carotenoids from oleaginous yeast. Separation and Purification Technology, v.257, p.117946, 2021. (DOI:10.1016/j.seppur.2020.117946

Liu, Z; Feist, AM; Dragone, GMussatto, SI. Lipid and carotenoid production from wheat straw hydrolysates by different oleaginous yeasts. Journal of Cleaner Production, v.249, p.119308, 2020. (DOI:10.1016/j.jclepro.2019.119308)

Castro, R; Ferreira, I; Roberto, I; Mussatto, SI. Isolation and physicochemical characterization of different lignin streams generated during the second-generation ethanol production process. International Journal of Biological Macromolecules, v.129, p.497-510, 2019. (DOI:10.1016/j.ijbiomac.2019.01.148)

Bonfiglio, F; Cagno, M; Rey, F; Torres, M; Böthig, S; Menéndez, P; Mussatto, SI. Pretreatment of switchgrass by steam explosion in a semi-continuous pre-pilot reactor. Biomass and Bioenergy, v.121, p.41-47, 2019. (DOI:10.1016/j.biombioe.2018.12.013)

Bussamra, B; Gomes, J; Freitas, S; Mussatto, SI; da Costa, A; van der Wielen, L; Ottens, M. A robotic platform to screen aqueous two-phase systems for overcoming inhibition in enzymatic reactions. Bioresource Technology, v.280, p.37-50, 2019. (DOI:10.1016/j.biortech.2019.01.136)

Qin, FJohansen, AMussatto, SI. Evaluation of different pretreatment strategies for protein extraction from brewer’s spent grains. Industrial Crops and Products, v.125, p.443-453, 2018. (DOI:10.1016/j.indcrop.2018.09.017

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